OVERVIEW OF OUR INTEGRATED SYSTEMS BIOLOGY APPROACH
We are working towards molecular-based disease stratification.
Our general approach involves correlating clinical, molecular, and histopathologic phenotyping, along with validation in model systems.
RESEARCH NEWS
Michigan Health Lab features our COVID-19 research
Dr. Kretzler co-leads Kidney-chip testing with UW School of Medicine
amfAR Funds Dr. Matthias Kretzler’s Crucial Research on New Treatments for COVID-19
NeuroNetwork for Emerging Therapies Mini Symposium: Complications of COVID-19
The Value of Kidney Biopsies to Empower New Discoveries in Diabetic Kidney Disease: Insight into COVID-19 kidney damage
SARS-CoV-2 receptor networks in diabetic kidney disease, BK-Virus nephropathy and COVID-19 associated acute kidney injury [KI in review]
Making patients resilient to COVID-19: Lessons to be learned from kidney single cell analysis
Matthias Kretzler presents an infrastructure to study a specific set of kidney rare diseases at Rare Disease Day.
Dr. Kretzler presented an introduction to the framework infrastructure used to study a specific set of kidney rare diseases at the Rare Disease Day conference last month.
Watch his presentation here.
Single Cell RNAseq Data Identifies Potential Endothelial Marker of FSGS Remission
The Kidney Precision Medicine Project (KPMP) and the Nephrotic Syndrome Study Network (NEPTUNE) recently published a landmark study in the journal JCI Insight. This work highlights the relevance of a new and emerging technology in exposing underlying mechanisms involved in kidney disease progression.
How the UMMS Central Biorepository Can Benefit Your Research
University of Michigan Medical School Office of Research recently published a video featuring the UMMS Central Biorepository (CBR). Director Victoria Blanc, Ph.D., walks through the process of accessing and storing biospecimens and MiKTMC’s Matthias Kretzler, MD speaks about how the samples from our cohort study networks across the world are managed using the CBR.